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Gynostemma pentaphyllum extract
Date:  2020-3-28  Click: 54 
 
Gynostemma pentaphyllum extract

Synonyms:

JIAOGULAN, GYNOSTEMMA PLANT EXTRACT, GYPENOSIDES 40% BY UV; GYNOSTEMMA PLANT EXTRACT, GYPENOSIDES 80% BY UV; GYNOSTEMMA PLANT EXTRACT, GYPENOSIDES 20% BY UV; GYNOSTEMMA PLANT EXTRACT, GYPENOSIDES 60% BY UV; GYNOSTEMMA PLANT EXTRACT, GYPENOSIDES 95% BY UV; GYNOSTEMMA PLANT EXTRACT, GYPENOSIDES 98% BY UV; GYPSOSIDE; Gynostemma Pentaphyllum P.E; pentopyranosyl-(1->3)-6-deoxyhexopyranosyl-(1->4)-[pentopyranosyl-(1->3)pentopyranosyl-(1->2)]-6-deoxy-1-O-(3-{[hexopyranosyl-(1->4)hexopyranosyl-(1->4)-[pentopyranosyl-(1->3)]hexopyranuronosyl]oxy}-23,28-dioxoolean-12-en-28-yl)hexopyranose

CAS no. : 15588-68-8
Molecular formula: C80H126O44
Molecular weight: 1791.83

Appearance: light yellow powder

Plant name:  gynostemma pentaphyllum, alias seven leaf gall, five leaf ginseng, small bitter medicine, male pot bottom, lobular five claw dragon, etc
Specification: 40%, 80%, 90%, 98%
Source:cucurbit, Gynostemma pentaphyllum (Thunb.) dried whole grass of Makino. Gynostemma pentaphyllum alias seven leaf gall, small peony cloud, pot bottom, rooting everywhere. Gynostemma pentaphyllum is a perennial herbaceous vine of the cucurbitaceae family. Bird toes compound leaves alternate, tendrils in axils, lobules often 5 ~ 7. Flowers unisexual, dioecious; Calyx and corolla lobes 5; The male flowers consist of round vertebral inflorescence, inflorescence axis slender, much branched, filaments short, united into column, anthers growing on apex; The female flowers are panicles and shorter than the male ones. Ovary inferior, globose, 2 - to 3-locular, style 3, short and divided, stigma 2-lobed, berry.
Resource distribution:

There are 13 known species of gynostemma pentaphyllum in the world. China accounted for 11 species, widely distributed in the south of the tianqinling vast provinces. Mainly grows in the altitude of 300-3200 meters valley dense forest, hills, slopes and stone mountain areas of the dank.
Quality standard: gynostemma pentaphyllum saponin A content as the standard. (there are ministry of health standards)

Health Benefits

Research into the health benefits of jiaogulan is limited to small clinical trials and laboratory studies. While the research shows promise, it is too soon to recommend jiaogulan as a treatment for any health condition.

Diabetes

Several studies suggest jiaogulan may help control diabetes. While much of the research has been limited to animal studies, a small clinical trial published in Hormone and Metabolic Research in 2010 found the herb may significantly reduce blood sugar levels in patients with type 2 diabetes.

Researchers assigned 24 diabetes patients to receive either 6 grams of jiaogulan tea or a placebo daily. After 12 weeks of treatment, subjects in the jiaogulan group showed greater improvement in blood sugar levels and insulin sensitivity than the control group. On average, the treated group saw a 54 mg/dL (3 mmol/L) reduction in fasting blood glucose readings and a 2-percentage-point drop in A1c levels.

Previous research on jiaogulan and diabetes includes an animal-based study published in the Journal of Pharmacy & Pharmaceutical Sciences in 2006, which tested the herb's effects on diabetic rats and found that it helped reduce blood sugar levels and lower LDL ("bad") cholesterol. 

In addition, a 2008 study on mine published in the Journal of Medicinal Fooddetermined that jiaogulan may help regulate blood sugar by altering activity in certain liver enzymes. While jiaogulan shows potential for treating type 2 diabetes, more research is needed before it can be recommended.

Obesity

Jiaogulan may have anti-obesity effects, according to a study published in the journal Obesity in 2013.

Using a jiaogulan extract known as actiponin, researchers assigned 80 obese patients to receive either 450 mg actiponin or a placebo daily for 12 weeks. At the end of the study, the jiaogulan group showed a significantly greater decrease in weight, abdominal fat, body fat mass, and body mass index compared to the placebo group.

Stress

Jiaogulan is one of many adaptogenic herbs said to relieve stress. An animal-based study published in the journal Molecules in 2013 indicates that jiaogulan may help protect against stress-related anxiety disorders. In tests on mice, the study's authors observed that jiaogulan helped inhibit stress-induced anxiety, possibly by influencing activity in certain brain cells involved in regulating mood.

Asthma

Jiaogulan may fight asthma, suggests an animal-based study published in the American Journal of Chinese Medicine in 2008. The study's authors looked at jiaogulan's effects on mice, finding that the herb helped reduce the airway inflammation associated with asthma.

Possible Side Effects

Jiaogulan is generally regarded as safe, though it may cause side effects including nausea and an increase in bowel movements.

People with diabetes who are taking insulin or other blood-sugar-lowering medications should use jiaogulan with caution, as it may lead to hypoglycemic episodes.

There's also some concern that jiaogulan may inhibit blood clotting, and therefore cause harm to people with blood conditions and/or those taking anticoagulants or antiplatelet agents. Due to jiaogulan's possible effects on blood clotting, it's also crucial to avoid the use of this herb prior to undergoing surgery.

Jiaogulan may have an impact on the immune system. People with anti-immune diseases such as lupus, multiple sclerosis, and rheumatoid arthritis should avoid using the herb until more research is done.

Also, the safety of jiaogulan in pregnant or nursing women has not been established and it should not be used.

Selection, Preparation, and Storage

Jiaogulan is sold in tea, powder, and capsule form and available in many natural-foods stores, stores specializing in herbal products or Chinese medicine, and online. It is available as a stand-alone or in herbal formulations.

As a tea, jiaogulan is caffeine-free and tastes similar to a mild green tea with a slightly bittersweet flavor. It can be blended with other teas, such as jasmine, or enjoyed on its own.

There is no standard dosage for jiaogulan, although alternative health practitioners typically recommend two to four cups a day.








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